Clozapine Response in Schizophrenia and Hematological Changes
نویسندگان
چکیده
منابع مشابه
Response to clozapine in a clinically identifiable subtype of schizophrenia.
BACKGROUND Genetic testing in psychiatry promises to improve patient care through advances in personalised medicine. However, there are few clinically relevant examples. AIMS To determine whether patients with a well-established genetic subtype of schizophrenia show a different response profile to the antipsychotic clozapine than those with idiopathic schizophrenia. METHOD We retrospectivel...
متن کاملClozapine in Treatment of Schizophrenia
The introduction of clozapine for the treatment of non responsive patients with schizophrenia has determined a real hope among patients, families and psychiatrists. This treatment is available that appears to be more effective than the standard or typical neuroleptics for many such treatment-resistant schizophrenic patients. A growing number of reports suggest that clozapine may also have a rol...
متن کاملClozapine alone versus clozapine and risperidone for refractory schizophrenia.
BACKGROUND The treatment of schizophrenia with multiple antipsychotic drugs is common, but the benefits and risks are not known. METHODS In a randomized, double-blind study, we evaluated patients with schizophrenia and a poor response to treatment with clozapine. The patients continued to take clozapine and were randomly assigned to receive eight weeks of daily augmentation with 3 mg of rispe...
متن کاملManagement of clozapine-resistant schizophrenia
The incidence of treatment resistance in schizophrenia (failure to respond to antipsychotic therapy) is about 20%. Factors that may contribute to it include non-adherence (non-compliance) to treatment, comorbid conditions and medication side-effects. The National Institute for Clinical Excellence recommends that clozapine be used for schizophrenia resistant to another atypical antipsychotic. He...
متن کاملRefractory Schizophrenia, Clozapine and Epilepsy : Management Strategies
This case of refractory schizophrenia in a 28 year old male showed significant improvement with clozapine. But therapeutic doses of clozapine were associated with generalised tonic clonic seizures (GTCS). Addition of sodium valproate allowed adequate control of schizophrenic symptoms as well as seizures. EEG abnormality correlated surprisingly well with development of GTCS and subsequent improv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Psychopharmacology
سال: 2020
ISSN: 1533-712X,0271-0749
DOI: 10.1097/jcp.0000000000001329